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Stability and Antibacterial Activity of Cefepime during Continuous Infusion

Year: 2003

Type: article

Abstract: The stability of cefepime during simulated continuous infusion was determined with a motorized portable infusion pump worn over a period of 24 to 36 h. Susceptibility testing on cefepime solutions over time indicates that the degradation products do not exhibit antibacterial activity. Cefepime stability at 24 h following continuous infusion was 94.3% +/- 1.0%, which supports the use of continuous infusion.

Source: Antimicrobial Agents and Chemotherapy

DOI: 10.1128/aac.47.6.1991-1994.2003

Authors: Pål F. Sprauten, Paul M. Beringer, Stan G. Louie, Timothy W. Synold, Mark A. Gill

Institutions: University of Southern California, University of Oslo, City Of Hope National Medical Center

Language: English

Topic: Antibiotics Pharmacokinetics and Efficacy

Subfield: Pharmacology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2121753196

FWCI: 0.998

Cites: 18

Cited by: 38

Related to: 10