Work

Adult Neuroblastoma Complicated by Increased Intracranial Pressure: A Case Report and Review of the Literature

Year: 2014

Type: article

Abstract: Neuroblastoma is the third most commonly occurring malignancy of the pediatric population, although it is extremely rare in the adult population. In adults, neuroblastoma is often metastatic and portends an extremely poor overall survival. Our case report documents metastatic neuroblastoma occurring in a healthy 29-year-old woman whose course was complicated by an unusual presentation of elevated intracranial pressures. The patient was treated with systemic chemotherapy, I(131) metaiodobenzylguanidine (MIBG) radiotherapy, and autologous stem cell transplant (SCT). Unfortunately the patient's response to therapy was limited and she subsequently died. We aim to review neuroblastoma in the context of increased intracranial pressure and the limited data of neuroblastoma occurring in the adult population, along with proposed treatment options.

Source: Case Reports in Oncological Medicine

DOI: 10.1155/2014/341980

Authors: Patrick L. Stevens, Douglas B. Johnson, Mary Ann Thompson, Vicki L. Keedy, Haydar A. Frangoul, Kristen M. Snyder

Institutions: Monroe Carell Jr. Children's Hospital, Vanderbilt University Medical Center

Language: English

Topic: Neuroblastoma Research and Treatments

Subfield: Neurology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $790