Year: 2010
Type: article
Abstract: A major limitation of any type of microscope is the penetration depth in turbid tissue. Here, we demonstrate a fundamentally novel kind of fluorescence microscope that images through optically thick turbid layers. The microscope uses scattered light, rather than light propagating along a straight path, for imaging with subwavelength resolution. Our method uses constructive interference to focus scattered laser light through the turbid layer. Microscopic fluorescent structures behind the layer were imaged by raster scanning the focus.
Source: Optics Letters
DOI: 10.1364/ol.35.001245
Authors: Ivo M. Vellekoop, Christof M. Aegerter
Institution: University of Zurich
Language: English
Subfield: Atomic and Molecular Physics, and Optics
Field: Physics and Astronomy
Domain: Physical Sciences
Open Access status: green
Funders: Universität Zürich, SystemsX.ch
OpenAlex ID: W2122559905