Work

hmChIP: a database and web server for exploring publicly available human and mouse ChIP-seq and ChIP-chip data

Year: 2011

Type: article

Abstract: UNLABELLED: hmChIP is a database of genome-wide chromatin immunoprecipitation (ChIP) data in human and mouse. Currently, the database contains 2016 samples from 492 ChIP-seq and ChIP-chip experiments, representing a total of 170 proteins and 11 069 914 protein-DNA interactions. A web server provides interface for database query. Protein-DNA binding intensities can be retrieved from individual samples for user-provided genomic regions. The retrieved intensities can be used to cluster samples and genomic regions to facilitate exploration of combinatorial patterns, cell-type dependencies, and cross-sample variability of protein-DNA interactions. AVAILABILITY: http://jilab.biostat.jhsph.edu/database/cgi-bin/hmChIP.pl.

Source: Bioinformatics

DOI: 10.1093/bioinformatics/btr156

Authors: Li Chen, George Wu, Hongkai Ji

Institution: Johns Hopkins University

Language: English

Topic: Genomics and Chromatin Dynamics

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: hybrid

Estimated APC paid: $3,989

Funders: National Human Genome Research Institute, National Institute of General Medical Sciences