Work

targetHub: a programmable interface for miRNA–gene interactions

Year: 2013
Type: article
Abstract: MOTIVATION: With the expansion of high-throughput technologies, understanding different kinds of genome-level data is a common task. MicroRNA (miRNA) is increasingly profiled using high-throughput technologies (microarrays or next-generation sequencing). The downstream analysis of miRNA targets can be difficult. Although there are many databases and algorithms to predict miRNA targets, there are few tools to integrate miRNA-gene interaction data into high-throughput genomic analyses. RESULTS: We present targetHub, a CouchDB database of miRNA-gene interactions. TargetHub provides a programmer-friendly interface to access miRNA targets. The Web site provides RESTful access to miRNA-gene interactions with an assortment of gene and miRNA identifiers. It can be a useful tool to integrate miRNA target interaction data directly into high-throughput bioinformatics analyses. AVAILABILITY: TargetHub is available on the web at http://app1.bioinformatics.mdanderson.org/tarhub/_design/basic/index.html.
Language: English
Subfield: Cancer Research
Open Access status: bronze
OpenAlex ID: W2123215282
FWCI: 0.517
Cites: 17
Cited by: 18
Related to: 10