Drug–gene interactions and the search for missing heritability: a cross-sectional pharmacogenomics study of the QT interval
Year: 2013
Type: article
Study design: Observational Study
Source: The Pharmacogenomics Journal
DOI: 10.1038/tpj.2013.4
Authors: C L Avery, C M Sitlani, D E Arking, D K Arnett, J C Bis, E Boerwinkle, B M Buckley, Y-D Ida Chen, A J M de Craen, M Eijgelsheim, D Enquobahrie, D S Evans, I Ford, M E Garcia, V Gudnason, T B Harris, S R Heckbert, H Hochner, A Hofman, W-C Hsueh, A Isaacs, J W Jukema, P Knekt, J A Kors, B P Krijthe, K Kristiansson, M Laaksonen, Y Liu, X Li, P W MacFarlane, C Newton-Cheh, M S Nieminen, B A Oostra, G M Peloso, K Porthan, K Rice, F F Rivadeneira, J I Rotter, V Salomaa, N Sattar, D S Siscovick, P E Slagboom, A V Smith, N Sotoodehnia, D J Stott, B H Stricker, T Stürmer, S Trompet, A G Uitterlinden, C van Duijn, R G J Westendorp, J C Witteman, E A Whitsel, B M Psaty
Institutions: Bank of America, University of North Carolina at Chapel Hill, University of Washington, Johns Hopkins University, Johns Hopkins Medicine, University of Alabama at Birmingham, The University of Texas Health Science Center at Houston, University College Cork, Cedars-Sinai Medical Center, Leiden University Medical Center, Erasmus MC, California Pacific Medical Center, University of Glasgow, National Institutes of Health, National Institute on Aging, Icelandic Heart Association, Netherlands Consortium for Healthy Ageing, University of California, San Francisco, Centre for Medical Systems Biology, Erasmus University Rotterdam, Finnish Institute for Health and Welfare, Wake Forest University Health Sciences, Wake Forest University, Broad Institute, Harvard University, Massachusetts General Hospital, Massachusetts Institute of Technology, Helsinki University Hospital, Framingham Heart Study, Group Health Cooperative
Language: English
Subfield: Pharmacology
Domain: Life Sciences
Open Access status: green
Funders: Burroughs Wellcome Fund, Doris Duke Charitable Foundation, Massachusetts General Hospital, Massachusetts Institute of Technology, Wake Forest University, School of Medicine, Boston University, Foundation for Cardiovascular Research, University of Washington, Johns Hopkins University, Helsingin ja Uudenmaan Sairaanhoitopiiri, Cedars-Sinai Medical Center, Broad Institute, European Commission, University of Glasgow, University College Cork, Universiteit Leiden, ZonMw, Erasmus Universiteit Rotterdam, Academy of Finland, Erasmus Medisch Centrum, Nederlandse Organisatie voor Wetenschappelijk Onderzoek, Leids Universitair Medisch Centrum, Sydäntutkimussäätiö, Orionin Tutkimussäätiö, Terveyden ja hyvinvoinnin laitos, Centre for Medical Systems Biology, National Institutes of Health, University of North Carolina at Chapel Hill, University of California, San Francisco, Erasmus Universitair Medisch Centrum Rotterdam, National Institute on Aging, National Heart, Lung, and Blood Institute, National Human Genome Research Institute, National Institute of Diabetes and Digestive and Kidney Diseases, National Institute of Neurological Disorders and Stroke, National Center for Research Resources, National Center for Advancing Translational Sciences, Department of Medicine, University of California, San Francisco
Awards: G1002540797, G100949702, G1028935811, G1052397333, Mapping Genes for Atherosclerosis and Insulin Resistance, G1083180012, G109016790, G1135917780, Multi-Ethnic Study of Atherosclerosis (MESA) Study, G1177103769, G1189786236, G1220223050, G1224608327, G1243299691, G1261793039, Genetic Determinants of Visceral Adiposity, G1332411685, G1345547317, G1401438683, G1409423729, G1412333385, DYNAMICS OF HEALTH,AGING, AND BODY COMPOSITION, G1460387277, G1462415530, G1495020029, CHS-ULTRASOUND READING, G1527150935, CORONARY HEART DISEASE AND STROKE, G1691174148, UCLA Clinical and Translational Science Institute, G1727292203, G173303992, G1742450553, G1890355377, G1909643007, G1922428914, G1941623656, G1982334678, G2070131968, G2146332128, DYNAMICS OF HEALTH, AGING, AND BODY COMPOSITION, G2193588257, G2194386449, G2273823554, G236442059, G2450915342, G247538147, Institute for Clinical and Translational Research (UL1), G250621538, Exceptional Survival: Trajectories to Functional Aging (CHS All Stars), G2555954497, G2636403020, G2663518188, G274585943, G277826483, G2786044735, G2800149121, G2815873878, G2818629771, G2818913090, G2847759872, G2882309788, G2918387404, SUBCLINICAL CARDIOVASCULAR DISEASE STUDY--EBCT READING, G297113894, G301743239, G3041236093, G3042145041, WGA Study to Identify Genetic Variants Associated with CV Events in CHS, G3114902838, G3137375862, G3145043064, G3152385821, HEALTH ABC--COORDINATING UNIT, Prospective meta-analyses of drug-gene interactions: CHARGE GWAS consortium, G3169706684, G3205625555, UCLA Clinical and Translational Science Institute, G333228317, G3342643523, G3370719899, G3410686264, G3462919067, G3507024915, G3560915123, G3647016462, G36937976, G3839646794, G3860090032, CENTRAL BLOOD ANALYSIS LABORATORY FOR CHS, Predictors of Alheimers Disease in Mild Cognitive Impairment, G4012114008, G411331190, G4167445418, G4200864717, G423252844, G4429312988, G445457422, Subcortical Hyperintensities in Sleep Apnea Syndrome, G457330776, G4638838207, G4643595647, G4660668308, G4765588100, Genetic determinants of cardiac repolarization, G4824283243, G494123624, G4987078009, G4993141604, G5074086979, G5125936451, G5164707915, G5167412771, G5281659474, G536099884, G537455924, G5386252567, Genome-Wide Association for Loci Influencing CHD and Other Heart, Lung and Blood, G5457026379, G5479317095, G552624687, G5540580309, Epidemiology of Venous Thrombosis and Pulmonary Embolism, G567847597, G573134505, G5755700318, G581554933, G5909482378, CHS Events Follow-up Study, G61834786, G619118814, G6195637971, G6226795708, Predictors of Alzheimers Disease in Mild Cognitive Impairment, Enumerating the Community Burden of Heart Failure, G6361934619, G6401035755, The Framingham Heart Study, G6548750934, G6552090923, G670738241, SNP HEALTH ASSOCIATION RESOURCE (SHARE), G6832344490, G687544517, G6902273418, G693548699, G7007046788, G7035200923, G7093047072, G716312657, MESA, G7505613430, CHS RETINAL READING CENTER, General Clinical Research Center, G764651519, G766700449, G766843672, G777822606, CHS Events Follow-up Study, G7999488110, G80149192, G806768229, G8068269535, G820615960, G8260701975, G8267674335, G831026002, G8392411440, G8506930532, G8593276544, G859984287, G861947890, CHS-Transition Phase -268055222, G870807107, G878552033, G8892155751, G8958082622, G9000015621, G9000018826, G9000027259, G9000030080, G9000050378, G9000065537, G9000065698, G9000069887, G9000112759, G9000124674, G9000140433, G9000143860, G9000145448, G9000155493, G9000159977, G9000239991, G9000294005, G9000354881, Diabetes Research Center (DRC), From GWAS loci to blood pressure genes, variants & mechanisms - Renewal, G905887895, G931818222, G945304896, G960597250, G991334795
OpenAlex ID: W2123597934