Work

Peptide-amphiphile nanofibers: A versatile scaffold for the preparation of self-assembling materials

Year: 2002

Type: article

Abstract: Twelve derivatives of peptide-amphiphile molecules, designed to self-assemble into nanofibers, are described. The scope of amino acid selection and alkyl tail modification in the peptide-amphiphile molecules are investigated, yielding nanofibers varying in morphology, surface chemistry, and potential bioactivity. The results demonstrate the chemically versatile nature of this supramolecular system and its high potential for manufacturing nanomaterials. In addition, three different modes of self-assembly resulting in nanofibers are described, including pH control, divalent ion induction, and concentration.

Source: Proceedings of the National Academy of Sciences

DOI: 10.1073/pnas.072699999

Authors: Jeffrey D. Hartgerink, Elia Beniash, Samuel I. Stupp

Institution: Northwestern University

Language: English

Topic: Supramolecular Self-Assembly in Materials

Subfield: Biomaterials

Field: Materials Science

Domain: Physical Sciences

Open Access status: green

OpenAlex ID: W2123692136

FWCI: 15.91

Cites: 49

Cited by: 1,241

Related to: 10