Microfluidic assembly of multistage porous silicon–lipid vesicles for controlled drug release
Year: 2014
Type: review
Abstract: A reliable microfluidic platform for the generation of stable and monodisperse multistage drug delivery systems is reported. A glass-capillary flow-focusing droplet generation device was used to encapsulate thermally hydrocarbonized porous silicon (PSi) microparticles into the aqueous cores of double emulsion drops, yielding the formation of a multistage PSi-lipid vesicle. This composite system enables a large loading capacity for hydrophobic drugs.
Source: Lab on a Chip
DOI: 10.1039/c3lc51260f
Institutions: University of Helsinki, Harvard University, University of Turku
Language: English
Subfield: Biomedical Engineering
Field: Engineering
Domain: Physical Sciences
Open Access status: hybrid
OpenAlex ID: W2123822194