POLG1 in idiopathic Parkinson disease
Year: 2006
Type: article
Study design: Observational Study
Abstract: We studied POLG1 in 140 UK patients with idiopathic Parkinson disease (PD) and 279 Italian patients with PD and compared them to a UK control group (n = 207) and an Italian control group (n = 285). Our observations do not support a role for common POLG1 genetic variants in PD and indicate that dominant POLG1 mutations are a rare cause of parkinsonism in the general population.
Source: Neurology
Institution: Newcastle University
Language: English
Subfield: Clinical Neurology
Field: Medicine
Domain: Health Sciences
Open Access status: green
Funder: Fondazione Telethon
OpenAlex ID: W2123839204