Fatty liver in lean patients: is it a different disease?
Year: 2012
Type: article
Abstract: Nonalcoholic fatty liver disease (NAFLD) has widely been considered a manifestation of metabolic syndrome in close relation to obesity [1]. In fact, although obesity is undoubt-edly one of the main risk factors for fatty liver, since its first description it is known that it can also occur in lean subjects. Studies in the Occident, with liver histology performed in subsets representative of the general population, as for example liver donors and automobile crash victims, among others, have roughly found hepatic steatosis in 15 % of non-obese subjects, as opposed to 65 % and 85 % in obese and morbid obese, respectively [2,3]. In fact, the majority of patients with steatosis are either overweight or obese [4]. The reality of developing countries seems to be different, with a recent study in India showing that in a rural population with low prevalence of NAFLD, 75 % of NAFLD patients had a body mass
Source: Europe PMC (PubMed Central)
Language: English
Subfield: Hepatology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W2124095500