Work

Organotrifluoroborates and Monocoordinated Palladium Complexes as Catalysts—A Perfect Combination for Suzuki–Miyaura Coupling

Year: 2009

Type: article

Abstract: Monocoordinated palladium catalysts derived from sterically hindered, electron-rich phosphines or N-heterocyclic carbenes have revolutionized the Suzuki-Miyaura coupling reaction. The emergence of organotrifluoroborates has provided important new perspectives for the organoboron component of these reactions. In combination, these two components prove to be extraordinarily powerful partners for cross-coupling reactions.

Source: Angewandte Chemie International Edition

DOI: 10.1002/anie.200904306

Authors: Gary A. Molander, Belgin Canturk

Institution: University of Pennsylvania

Language: English

Topic: Catalytic Cross-Coupling Reactions

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: green

Funders: National Institute of General Medical Sciences, National Center for Research Resources

Awards: Agilent 5973 GC/MS System, Novel Organoboron Chemistry Utilizing Tetrahydroxydiborane, Organotrifluoroborates in Selective Organic Synthesis, Catalytic Processes for Selective Organic Synthesis, Novel Boronic Acids for Pilot-Scale Screening