Work

Using biosensors to detect the release of serotonin from taste buds during taste stimulation.

Year: 2005

Type: article

Abstract: CHO cells transfected with high-affinity 5HT receptors were used to detect and identify the release of serotonin from taste buds. Taste cells release 5HT when depolarized or when stimulated with bitter, sweet, or sour tastants. Sour- and depolarization-evoked release of 5HT from taste buds is triggered by Ca2+ influx from the extracellular fluid. In contrast, bitter- and sweet-evoked release of 5HT is triggered by Ca2+ derived from intracellular stores.

Source: PubMed

Authors: Y J Huang, Y Maruyama, K S Lu, E Pereira, I Plonsky, J E Baur, D Wu, S D Roper

Institution: University of Miami

Language: English

Topic: Biochemical Analysis and Sensing Techniques

Subfield: Nutrition and Dietetics

Field: Nursing

Domain: Health Sciences

Open Access status: green

Funder: National Institute on Deafness and Other Communication Disorders

Awards: A new method to measure taste bud function, A new method to measure taste bud function

OpenAlex ID: W2125119636

FWCI: 1.606

Cites: 45

Cited by: 19

Related to: 10