Work

A novel pyridopyrimidine inhibitor of abl kinase is a picomolar inhibitor of Bcr-abl-driven K562 cells and is effective against STI571-resistant Bcr-abl mutants.

Year: 2003

Type: article

Source: PubMed

Authors: David R Huron, Mercedes E Gorre, Alan J Kraker, Charles L Sawyers, Neal Rosen, Mark M Moasser

Institution: Memorial Sloan Kettering Cancer Center

Language: English

Topic: Chronic Myeloid Leukemia Treatments

Subfield: Hematology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: closed

Funder: National Institute of General Medical Sciences

Award: Research Tranining in Cellular and Molecular Biology

OpenAlex ID: W2125337971

FWCI: 9.553

Cites: 22

Cited by: 118

Related to: 10