Year: 2008
Type: review
Abstract: Near-infrared fluorescent (NIRF) materials are promising labeling reagents for sensitive determination and imaging of biological targets. In the near-infrared region biological samples have low background fluorescence signals, providing high signal to noise ratio. Meanwhile, near-infrared radiation can penetrate into sample matrices deeply due to low light scattering. Thus, in vivo and in vitro imaging of biological samples can be achieved by employing the NIRF probes. To take full advantage of NIRF materials in the biological and biomedical field, one of the key issues is to develop intense and biocompatible NIRF probes. In this review, a number of NIRF materials are discussed including traditional NIRF dye molecules, newly developed NIRF quantum dots and single-walled carbon nanotubes, as well as rare earth metal compounds. The use of some NIRF materials in various nanostructures is illustrated. The enhancement of NIRF using metal nanostructures is covered as well. The fluorescence mechanism and bioapplications of each type of the NIRF materials are discussed in details.
Source: Sensors
DOI: 10.3390/s8053082
Authors: Carrie Amiot, Shuping Xu, Song Liang, Lingyun Pan, Julia Zhao
Institutions: University of North Dakota, Jilin University
Language: English
Subfield: Materials Chemistry
Field: Materials Science
Domain: Physical Sciences
Open Access status: gold
Estimated APC paid: $3,137
Awards: THE NORTH DAKOTA DOE EPSCOR IIP PHASE 2: PERFORMANCE IMPACTS OF IMPURITIES IN CLEAN COAL SYSTEMS EQU, G222768804, Surface Functionalized Nanoparticles for Enrichment and Detection of Trace Analytes, THE NORTH DAKOTA DOE EPSCOR INFRASTRUCTURE IMPROVEMENT PROGRAM: ADVANCES IN THE FUNDAMENTAL UNDERSTANDING OF COAL COMBUSTION EMISSION MECHANISMS
OpenAlex ID: W2125455204