Work

Protein Coagulation and Its Reversal

Year: 1930

Type: article

Abstract: 1. By a procedure involving the use of acid acetone hemoglobin may be rapidly separated into a precipitate of denatured globin and an acetone solution of heme. 2. By neutralization procedures the denatured globin may be largely converted into a soluble, apparently native form which can combine with heme to form hemoglobin. 3. The heme may be obtained in acetone-free, slightly alkaline solution without the use of strong alkali which may modify the heme.

Source: The Journal of General Physiology

DOI: 10.1085/jgp.13.4.469

Authors: M. L. Anson, A. E. Mirsky

Institution: Rockefeller University Hospital

Language: English

Topic: Hemoglobin structure and function

Subfield: Biochemistry

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

OpenAlex ID: W2125550241

FWCI: 2.702

Cites:

Cited by: 494

Related to: 10