Work

Validation of the AKIN criteria definition using high-resolution ICU data from the MIMIC-II database

Year: 2011

Type: article

Abstract: Recently the Acute Kidney Injury (AKI) Network proposed criteria for the definition of AKI in the critically ill. The minimum hourly urine output rate used to define oliguria (< 0.5 ml/kg/hour) is based exclusively on clinical experience and animal models, not on clinical investigation. Moreover, the minimum duration of oliguria (6 hours) is based on clinical experience and was never experimentally determined. We used a massive database of ICU patients (MIMIC) to continuously vary the observation period and threshold of urine output measurements to determine optimal AKI definitions for improved in-hospital mortality prediction.

Source: Critical Care

DOI: 10.1186/cc9525

Authors: T Mandelbaum, DJ Scott, J Lee, RG Mark, MD Howell, A Malhotra, D Talmor

Institutions: Beth Israel Deaconess Medical Center, Harvard University, Harvard–MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Brigham and Women's Hospital

Language: English

Topic: Acute Kidney Injury Research

Subfield: Nephrology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $4,190

Funders: Univerzita Karlova v Praze, Intensive Care Foundation, Fundação de Amparo à Pesquisa do Estado de São Paulo, ZonMw, Faculdade de Medicina da Universidade de São Paulo, National Institutes of Health, National Health and Medical Research Council

Awards: Comparacao de reposicao volemica guiada por variacao de pressao de pulso por parametros tradicionais em modelos suinos de choque hemorragico e choque hemorragico com endotoxemia., G9000173989

OpenAlex ID: W2125927103

FWCI:

Cites: 101

Cited by: 1

Related to: 10