Year: 2004
Type: dissertation
Abstract: 9 1. REVIEW OF THE LITERATURE 9 1.1. Ectodermal Organ Development 9 1.1.1. Origin of ectoderm 9 1.1.2. Common mechanisms in ectoderm 10 al organ development 1.1.3. Introduction to selected molecules with a central role in ectodermal organ development 10 1.1.3.1. Fgf, Bmp, Wnt, Shh pathways 10 1.1.3.2. Notch Pathway 13 1.1.3.3. Tnfs 16 1.1.3.3.1.Ectodysplasin pathway 18 1.1.4. Tooth development 19 1.1.5. Hair, nail and sweat gland development 24 1.1.6. Mammary, sebaceous and salivary gland development 28 1.2. Stem Cells 29 2. AIMS OF THE STUDY 31 3. MATERIALS AND METHODS 31 4. RESULTS AND DISCUSSION 32 4.1. Notch pathway molecules are associated with stem cell regulation in the postnatal mouse incisor 32 4.2. Fgfs regulate stem cell compartment and Lfng expression in postnatal mouse incisor 34 4.3. Notch pathway at the bud-to-cap stage transition of developing molar 36 4.4. Hes5 is upregulated in the isolated epithelium 38 4.5. Overexpression of Eda-A2 39 4.6. Overexpression of Eda-A1 39 4.6.1. Characteristics of the adult phenotype 40 4.6.2. Ectodermal placode formation 41 5. CONCLUDING REMARKS 44
Source: Työväentutkimus Vuosikirja
Author: Tuija Mustonen
Language: English
Subfield: General Dentistry
Field: Dentistry
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W2126087021