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Protein Microarray for Profiling Antibody Responses to Yersinia pestis Live Vaccine

Year: 2005

Type: article

Abstract: A protein microarray representing 149 Yersinia pestis proteins was developed to profile antibody responses in EV76-immunized rabbits. Antibodies to 50 proteins were detected. There are 11 proteins besides F1 and V antigens to which the predominant antibody response occurred, and these proteins show promise for further evaluation as candidates for subunit vaccines and/or diagnostic antigens.

Source: Infection and Immunity

DOI: 10.1128/iai.73.6.3734-3739.2005

Authors: Bei Li, Lingxiao Jiang, Qifeng Song, Junxin Yang, Zeliang Chen, Zhaobiao Guo, Dongsheng Zhou, Zongmin Du, Yajun Song, Jin Wang, Hongxia Wang, Shouyi Yu, Jian Wang, Ruifu Yang

Institutions: Academy of Military Medical Sciences, National Center of Biomedical Analysis, Southern Medical University, Chinese Academy of Sciences, Beijing Institute of Genomics

Language: English

Topic: Yersinia bacterium, plague, ectoparasites research

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funder: National Natural Science Foundation of China

Award: 鼠疫疫苗的相关基础研究

OpenAlex ID: W2126095396

FWCI: 5.374

Cites: 37

Cited by: 89

Related to: 10