Work

Synthesis of texaphyrin conjugates

Year: 2004

Type: article

Abstract: This paper summarizes recent synthetic efforts devoted to the generation of new, second-generation texaphyrin-type drugs, specifically species that involve known or potential anticancer agents covalently attached to a tumor-localizing texaphyrin core. Particular emphasis will be placed on the strategies needed to prepare such systems, as well as on the choice of active group being subject to attachment.

Source: Pure and Applied Chemistry

DOI: 10.1351/pac200476020365

Authors: D. J. Magda, Z. Wang, Nikolay Gerasimchuk, W.-H. Wei, P. Anzenbacher, J. L. Sessler

Institutions: Pharmacyclics (United States), The University of Texas at Austin

Language: English

Topic: Porphyrin and Phthalocyanine Chemistry

Subfield: Materials Chemistry

Field: Materials Science

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: bronze

Funder: National Institutes of Health