Distinction between mouse DNA polymerases α and β by tryptic peptide mapping
Year: 1980
Type: article
Abstract: Results presented here and in a previous paper (Tanabe et al. (1979) Biochemistry 18, 3401--3406) indicate that mouse beta-polymerase is a single polypeptide with an apparent molecular weight of 40,000. This polypeptide has now been analyzed by tryptic peptide mapping. Comparison of the results with identical analysis of mouse alpha-polymerase reveals that the tryptic peptides derived from the two enzymes are different. These results indicate that beta-polymerase is neither a subunit of alpha-polymerase nor a proteolytic degradation product of alpha-polymerase.
Source: Nucleic Acids Research
Authors: S.R. Planck, K. Tanabe, S.H. Wilson
Institutions: National Institutes of Health, National Cancer Institute
Language: English
Topic: DNA Repair Mechanisms
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W2126446546