Work

Use of a Surrogate Chimeric Virus To Detect West Nile Virus-Neutralizing Antibodies in Avian and Equine Sera

Year: 2008

Type: article

Abstract: A chimeric yellow fever virus/West Nile virus (WNV) was compared to WNV alone as a biosafety level 2 reagent in the plaque reduction neutralization test for determining WNV infection histories. Concordance was 96.3% among 188 avian and equine serum samples. Neutralizing antibody titers were frequently more than twofold lower with the chimera.

Source: Clinical and Vaccine Immunology

DOI: 10.1128/cvi.00220-08

Authors: Nicholas Komar, Stanley Langevin, Thomas P. Monath

Institution: Centers for Disease Control and Prevention

Language: English

Topic: Mosquito-borne diseases and control

Subfield: Public Health, Environmental and Occupational Health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W2126654954

FWCI: 2.309

Cites: 12

Cited by: 16

Related to: 10