Year: 2008
Type: review
Abstract: One of the molecular responses which mostly contribute to the physiological plasticity of bivalvesis the heat shock response mediated by heat shock proteins (HSP). Variations of HSP response wereobserved under environmental conditions, correlated with differences in environmental temperatureand degree of heterogeneity across geographic thermal gradients and through time. Laboratoryexperiments characterized the expressions of different protein isoforms and coding genes, which areinduced by heat as a prototypical stimulus. Nevertheless, other physical and chemical factorssignificantly induce HSP gene and protein expressions in bivalves, that can be different depending ontissues and the nature of the insult. Multiple alignments of the deduced amino acid sequencesindicated that the bivalve HSP70 proteins share common structural and evolutionary features with themammalian HSP70, while some appear to be exclusive. The rate at which new findings are maderegarding the bivalve HSP response is still increasing. However, some major questions remainunanswered. Among them, the possibility that the bivalve HSP response is related to cell signallingpathways and acts as a component of the acute systemic response to stress is also discussed in thisreview.
Source: Invertebrate survival journal
Authors: E Fabbri, P Valbonesi, S Franzellitti
Institution: University of Bologna
Language: English
Topic: Heat shock proteins research
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: diamond
OpenAlex ID: W2126715719