Microfabricating high-aspect-ratio structures in polyurethane-methacrylate (PUMA) disposable microfluidic devices
Year: 2009
Type: article
Abstract: We recently reported a new UV-curable polyurethane-methacrylate (PUMA) resin that has excellent qualities as a disposable microfluidic substrate for clinical diagnostic applications. This article discusses strategies to improve the production yield of PUMA chips that contain dense and high-aspect-ratio features, which presents unique challenges in demolding and bonding steps. These fabrication improvements were deployed to produce a microfiltration device that contained closely spaced and high-aspect-ratio columns, suitable for retaining and concentrating cells or beads from a highly diluted suspension.
Source: Lab on a Chip
DOI: 10.1039/b902124h
Authors: Jason S. Kuo, Yongxi Zhao, Laiying Ng, Gloria S. Yen, Robert M. Lorenz, David S. W. Lim, Daniel T. Chiu
Institution: University of Washington
Language: English
Subfield: Biomedical Engineering
Field: Engineering
Domain: Physical Sciences
Open Access status: green
OpenAlex ID: W2126977206