Year: 2010
Type: article
Study design: Observational Study
Abstract: Because there is little routine tuberculosis (TB) screening in Mexico, the prevalence of latent TB infection (LTBI) is unknown. In the context of an increasing HIV epidemic in Tijuana, Mexico, understanding prevalence of LTBI to anticipate emergence of increased LTBI reactivation is critical. Therefore, we recruited injection drug users, noninjection drug users, female sex workers, and homeless persons for a study involving risk assessment, rapid HIV testing, and TB screening. Of 503 participants, the overall prevalences of TB infection, HIV infection, and TB/HIV co-infection were 57%, 4.2%, and 2.2%, respectively; no significant differences by risk group (p>0.05) were observed. Two participants had TB (prevalence 398/100,000). Incarceration in Mexico (odds ratio [OR] 2.28), age (OR 1.03 per year), and years lived in Tijuana (OR 1.02 per year) were independently associated with TB infection (p<0.05). Frequent LTBI in marginalized persons may lead to increases in TB as HIV spreads.
Source: Emerging infectious diseases
Language: English
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
Funders: United States Agency for International Development, California HIV/AIDS Research Program, National Institutes of Health, University of California, San Diego, National Institute of Mental Health, National Institute on Drug Abuse, National Institute of Allergy and Infectious Diseases, National Institute on Minority Health and Health Disparities
Awards: G1082375795, G1642057017, G166978917, G1766461084, G1808465013, G1888270160, G2510954654, G2693678250, G2811970292, Binational Transmission of Multidrug-Resistant Tuberculosis, California & Mexico, G5397292185, G672390936, Impact of Drug Policy Reform on the HIV Risk Environment among IDUs in Tijuana, Training Program in Substance Use, HIV and Related Infections, HOPE Training Grant
OpenAlex ID: W2127180629