Work

Thiol-addition reactions and their applications in thiol recognition

Year: 2013

Type: review

Abstract: Because of the biological importance of thiols, the development of probes for thiols has been an active research area in recent years. In this review, we summarize the results of recent exciting reports regarding thiol-addition reactions and their applications in thiol recognition. The examples reported can be classified into four reaction types including 1,1, 1,2, 1,3, 1,4 addition reactions, according to their addition mechanisms, based on different Michael acceptors. In all cases, the reactions are coupled to color and/or emission changes, although some examples dealing with electrochemical recognition have also been included. The use of thiol-addition reactions is a very simple and straightforward procedure for the preparation of thiol-sensing probes.

Source: Chemical Society Reviews

DOI: 10.1039/c3cs60055f

Authors: Caixia Yin, Fangjun Huo, Jingjing Zhang, Ramón Martínez-Máñez, Yutao Yang, Haigang Lv, Sidian Li

Institutions: Shanxi University, Universitat de València, Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine, Centro de Investigación Biomédica en Red, Universitat Politècnica de València

Language: English

Topic: Sulfur Compounds in Biology

Subfield: Biochemistry

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

OpenAlex ID: W2127282581

FWCI: 6.774

Cites: 134

Cited by: 555

Related to: 10