Year: 2014
Type: article
Abstract: Reading and language disorders are common childhood conditions that often co-occur with each other and with other neurodevelopmental impairments. There is strong evidence that disorders, such as dyslexia and Specific Language Impairment (SLI), have a genetic basis, but we expect the contributing genetic factors to be complex in nature. To date, only a few genes have been implicated in these traits. Their functional characterization has provided novel insight into the biology of neurodevelopmental disorders. However, the lack of biological markers and clear diagnostic criteria have prevented the collection of the large sample sizes required for well-powered genome-wide screens. One of the main challenges of the field will be to combine careful clinical assessment with high throughput genetic technologies within multidisciplinary collaborations.
Source: Genes
DOI: 10.3390/genes5020285
Language: English
Subfield: Developmental and Educational Psychology
Field: Psychology
Domain: Social Sciences
Open Access status: gold
Estimated APC paid: $3,137
Awards: G2436244107, The role of the KIAA0319 protein in neurodevelopment ., Investigation of the genetic causes of Specific Language Impairment (SLI) in an isolated Chilean population, Understanding the genetic basis of common human diseases: core funding for the Wellcome Trust Centre for Human Genetics., Understanding the genetic basis of common human diseases: core funding for the Wellcome Trust Centre for Human Genetics., G8975541179, Investigation of the roles of CMIP and ATP2C2 in Specific Language Impairment (SLI).
OpenAlex ID: W2127601221