Work

Biomolecular simulation and modelling: status, progress and prospects

Year: 2008

Type: review

Abstract: Molecular simulation is increasingly demonstrating its practical value in the investigation of biological systems. Computational modelling of biomolecular systems is an exciting and rapidly developing area, which is expanding significantly in scope. A range of simulation methods has been developed that can be applied to study a wide variety of problems in structural biology and at the interfaces between physics, chemistry and biology. Here, we give an overview of methods and some recent developments in atomistic biomolecular simulation. Some recent applications and theoretical developments are highlighted.

Source: Journal of The Royal Society Interface

DOI: 10.1098/rsif.2008.0105.focus

Authors: Marc W van der Kamp, Katherine E Shaw, Christopher J Woods, Adrian J Mulholland

Institution: University of Bristol

Language: English

Topic: Protein Structure and Dynamics

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

Funders: Engineering and Physical Sciences Research Council, Biotechnology and Biological Sciences Research Council