Work

Functional MRI of the lung using hyperpolarized 3‐helium gas

Year: 2004

Type: review

Abstract: Lung imaging has traditionally relied on x-ray methods, since proton MRI is limited to some extent by low proton density in the lung parenchyma and static field inhomogeneities in the chest. The relatively recent introduction of MRI of hyperpolarized noble gases has led to a rapidly evolving field of pulmonary MRI, revealing functional information of the lungs, which were hitherto unattainable. This review article briefly describes the physical background of the technology, and subsequently focuses on its clinical applications. Four different techniques that have been used in various human investigations are discussed: ventilation distribution, ventilation dynamics, and small airway evaluation using diffusion imaging and oxygen uptake assessment.

Source: Journal of Magnetic Resonance Imaging

DOI: 10.1002/jmri.20154

Authors: Edwin J.R. van Beek, Jim M. Wild, Hans‐Ulrich Kauczor, Wolfgang Schreiber, John P. Mugler, Eduard E. de Lange

Institutions: University of Sheffield, German Cancer Research Center, Johannes Gutenberg University Mainz, University of Virginia

Language: English

Topic: Atomic and Subatomic Physics Research

Subfield: Atomic and Molecular Physics, and Optics

Field: Physics and Astronomy

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: National Institutes of Health, National Heart, Lung, and Blood Institute