Work

Transition‐Metal‐Catalyzed Laboratory‐Scale Carbon–Carbon Bond‐Forming Reactions of Ethylene

Year: 2013

Type: review

Abstract: Ethylene, the simplest alkene, is the most abundantly synthesized organic molecule by volume. It is readily incorporated into transition-metal-catalyzed carbon-carbon bond-forming reactions through migratory insertions into alkylmetal intermediates. Because of its D2h symmetry, only one insertion outcome is possible. This limits byproduct formation and greatly simplifies analysis. As described within this Minireview, many carbon-carbon bond-forming reactions incorporate a molecule (or more) of ethylene at ambient pressure and temperature. In many cases, a useful substituted alkene is incorporated into the product.

Source: Angewandte Chemie International Edition

DOI: 10.1002/anie.201303916

Authors: Vaneet Saini, Benjamin J. Stokes, Matthew S. Sigman

Institution: University of Utah

Language: English

Topic: Organometallic Complex Synthesis and Catalysis

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: green

Funder: National Institute of General Medical Sciences

Awards: Pd(0)-Catalyzed Allylic C-H Functionalization Reactions of Homoallylic Tosylates, Pd-Catalyzed Olefin Functionalization Reactions for Organic Synthesis