“No Wash” Albumin-Dextran Dilution for Double-Unit Cord Blood Transplantation (DCBT) Is Safe with Appropriate Management and Results in High Rates of Sustained Donor Engraftment
Year: 2012
Type: article
Abstract: The wash of CB grafts involves additional product manipulation, risks cell loss, & delays time to infusion. We have previously reported that albumin-dextran dilution without centrifugation is feasible & safe in recipients of red blood cell (RBC) depleted DCBT > 20 kg. Concern remains, however, about the risk of severe infusion reactions. We now report our experience in 108 “no wash” DCBT recipients using RBC depleted units for the treatment of high-risk hematologic malignancies between 2/2006-8/2011.
Institution: Memorial Sloan Kettering Cancer Center
Language: English
Subfield: Hematology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Estimated APC paid: $3,650
OpenAlex ID: W2128710002