Work

A Statistical Multiprobe Model for Analyzing cis and trans Genes in Genetical Genomics Experiments With Short-Oligonucleotide Arrays

Year: 2005

Type: article

Abstract: Short-oligonucleotide arrays typically contain multiple probes per gene. In genetical genomics applications a statistical model for the individual probe signals can help in separating "true" differential mRNA expression from "ghost" effects caused by polymorphisms, misdesigned probes, and batch effects. It can also help in detecting alternative splicing, start, or termination.

Source: Genetics

DOI: 10.1534/genetics.105.045930

Authors: Rudi Alberts, Peter Terpstra, Leonid V Bystrykh, Gerald de Haan, Ritsert C Jansen

Institutions: University of Groningen, University Medical Center Groningen

Language: English

Topic: Gene expression and cancer classification

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: bronze

OpenAlex ID: W2128845545

FWCI: 2.51

Cites: 13

Cited by: 37

Related to: 10