Work

Emergence of KPC-Possessing Klebsiella pneumoniae in Brooklyn, New York: Epidemiology and Recommendations for Detection

Year: 2005

Type: article

Abstract: Among 257 isolates of Klebsiella pneumoniae collected in Brooklyn, NY, 24% were found to possess bla(KPC). Clinical microbiology laboratories that used automated broth microdilution systems reported 15% of the KPC-possessing isolates as susceptible to imipenem. The imipenem MIC was found to be markedly affected by the inoculum. For accurate detection of KPC-possessing K. pneumoniae, particular attention should be paid to proper inoculum preparation for broth-based susceptibility methods. In addition, using ertapenem or meropenem for class reporting of carbapenem susceptibility will improve detection.

Source: Antimicrobial Agents and Chemotherapy

DOI: 10.1128/aac.49.7.3018-3020.2005

Authors: Simona Bratu, Mohamad Mooty, Satyen Nichani, David Landman, Carl Gullans, Barbara Pettinato, Usha Karumudi, Pooja Tolaney, John Quale

Institutions: SUNY Downstate Health Sciences University, Kings County Hospital Center, Coney Island Hospital

Language: English

Topic: Antibiotic Resistance in Bacteria

Subfield: Molecular Medicine

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2129122982

FWCI: 10.29

Cites: 8

Cited by: 246

Related to: 10