Work

Reduction of ER stress via a chemical chaperone prevents disease phenotypes in a mouse model of primary open angle glaucoma

Year: 2015

Type: article

Abstract: An investigation by the University Health Network recently found that portions of the RT-PCR gels shown in Figure 1, B (PGK-1 panel) and C (FGFR1 panel), are duplicated in this publication and in a subsequent publication (1).The samples were labeled differently in the panels, and the marker was shifted in Figure 1B.The corresponding author has indicated that other data from the initial screen of these samples support the conclusions made in the paper; however, the original data for the RT-PCR gels shown in Figure 1 are no longer available.The JCI's policies prohibit data manipulation and data duplication.Therefore, the JCI is retracting this article.No issues have been raised in regard to any of the other data in this manuscript.

Source: Journal of Clinical Investigation

DOI: 10.1172/jci82799