Thymosin alpha1: isolation and sequence analysis of an immunologically active thymic polypeptide.
Year: 1977
Type: article
Abstract: The amino acid sequence of a biologically active polypeptide isolated from calf thymus, termed thymosin alpha1, has been determined. Thymosin alpha1 is a heat stable, highly acidic molecule composed of 28 amino acid residues. This peptide is one of several present in thymosin fraction 5 that may participate in the regulation, differentiation and function of thymus-dependent lymphocytes (T cells). A nomenclature for the family of polypeptides present in thymosin fraction 5 is suggested.
Authors: A L Goldstein, T L Low, M McAdoo, J McClure, G B Thurman, J Rossio, C Y Lai, D Chang, S S Wang, C Harvey, A H Ramel, J Meienhofer
Language: English
Topic: T-cell and B-cell Immunology
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: bronze
OpenAlex ID: W2129424218