Year: 2013
Type: article
Abstract: Biotargeted nanomedicines have captured the attention of academic and industrial scientists who have been motivated by the theoretical possibilities of the 'magic bullet' that was first conceptualized by Paul Ehrlich at the beginning of the 20th century. The Biotargeting Working Group, consisting of more than 50 pharmaceutical scientists, engineers, biologists and clinicians, has been formed as part of the National Cancer Institute's Alliance for Nanotechnology in Cancer to harness collective wisdom in order to tackle conceptual and practical challenges in developing biotargeted nanomedicines for cancer. In modern science and medicine, it is impossible for any individual to be an expert in every aspect of biology, chemistry, materials science, pharmaceutics, toxicology, chemical engineering, imaging, physiology, oncology and regulatory affairs. Drawing on the expertise of leaders from each of these disciplines, this commentary highlights six tenets of biotargeted cancer nanomedicines in order to enable the translation of basic science into clinical practice.
Source: Nanomedicine
DOI: 10.2217/nnm.13.3
Institutions: Harvard University, Dana-Farber Cancer Institute, National Institutes of Health, Office of the Director, National Cancer Institute, University of North Carolina at Chapel Hill, Johns Hopkins University, Johns Hopkins Medicine, National Cancer Institute, Frederick National Laboratory for Cancer Research, National Cancer Institute, University of Southern California, Children's Hospital of Los Angeles, University of Wisconsin–Madison, Stanford Medicine, Stanford University
Language: English
Subfield: Biomaterials
Field: Materials Science
Domain: Physical Sciences
Open Access status: green
OpenAlex ID: W2129895028