Work

A systematic comparative and structural analysis of protein phosphorylation sites based on the mtcPTM database

Year: 2007

Type: article

Abstract: mtcPTM is an online repository of human and mouse phosphosites in which data are hierarchically organized to preserve biologically relevant experimental information, thus allowing straightforward comparisons of phosphorylation patterns found under different conditions. The database also contains the largest available collection of atomic models of phosphorylatable proteins. Detailed analysis of this structural dataset reveals that phosphorylation sites are found in a heterogeneous range of structural and sequence contexts. mtcPTM is available on the web http://www.mitocheck.org/cgi-bin/mtcPTM/search.

Source: Genome biology

DOI: 10.1186/gb-2007-8-5-r90

Authors: José L Jiménez, Björn Hegemann, James RA Hutchins, Jan-Michael Peters, Richard Durbin

Institutions: Wellcome Sanger Institute, Research Institute of Molecular Pathology

Language: English

Topic: Advanced Proteomics Techniques and Applications

Subfield: Spectroscopy

Field: Chemistry

Domain: Physical Sciences

Open Access status: gold

Estimated APC paid: $5,490

Funders: Wellcome Trust, European Commission