A 3‐year‐ Old Girl With Altered Mental Status, Gait Difficulty, and Vomiting
Year: 2010
Type: article
Study design: Case Report
Abstract: We report a case of a 3-year-old girl with a 9-month history of focal neurologic finding and signs of increased intracranial pressure. Radiological imaging studies showed a minimally heterogeneous enhancing large tumor involving left parietal region and partly filling the left lateral ventricle. Microscopically, the tumor contained prominent small true rosettes set into areas of fibrillar neuropil-like matrix. Foci of cellular tumor with extensive apoptosis were present. The neuropil-like areas and true rosettes were positive for synaptophysin immunostain. The tumor was negative for GFAP and neurofilament protein immunostains. MIB-1 proliferation index was high focally approaching 80%.
Source: Brain Pathology
Authors: Ilya Lim, Irina Mikolaenko, Mark Cohen
Institutions: NYU Langone Health, Case Western Reserve University
Language: English
Subfield: Genetics (clinical)
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W2130006814