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A Longitudinal Examination of Physiological Regulation in Cocaine‐Exposed Infants Across the First 7 Months of Life

Year: 2009

Type: article

Abstract: This study examined the association between prenatal exposure to cocaine and physiological regulation across the first 7 months of age. Measures of respiratory sinus arrhythmia (RSA) were obtained from 169 (82 cocaine-exposed and 87 nonexposed) infants during baseline periods at 1 month and 7 months of age and during tasks designed to elicit positive and negative affect at 7 months of age. After controlling for maternal age, gestational age, and obstetrical risk, structural equation modeling indicated that the association between prenatal exposure to cocaine and baseline RSA at 7 months of age was direct even in the presence of an indirect effect through baseline RSA at 1 month of age. There were no indirect effects through maternal affect during mother-infant interactions assessed at 1 month of age. Analyses also indicated a direct association between prenatal exposure to cocaine and RSA regulation to negative affect at 7 months of age.

Source: Infancy

DOI: 10.1080/15250000802569660

Authors: Pamela Schuetze, Rina D. Eiden, Ellen P. Edwards

Institution: University at Buffalo, State University of New York

Language: English

Topic: Prenatal Substance Exposure Effects

Subfield: Pediatrics, Perinatology and Child Health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funder: National Institute on Drug Abuse