Work

Description of the thermotropic behavior of membrane bilayers in terms of raman spectral parameters - a 2-state model

Year: 1987

Type: article

Abstract: An analytical expression is developed for describing the thermotropic behavior of membrane bilayers as studied by Raman spectroscopy.The expression is derived from a two-state model of the main gel to liquid crystalline phase transition in lipid bilayers.Experimental data for a variety of diacylphosphatidylcholines and their derivatives have been fit by least squares to the two-state expression to within currently achievable measurement error.Numerical techniques have been developed for placing bounds on the parameters of the two-state model in situations of sparse data in the phase transition region.By fitting the model to the measured spectroscopic data, estimates of the extent of cooperativity in the phase transition can be obtained in a systematic manner.

Source: Journal of Research of the National Bureau of Standards

DOI: 10.6028/jres.092.012

Authors: W.H. Kirchhoff, I.W. Levin

Institutions: National Institute of Standards and Technology, National Institutes of Health

Language: English

Topic: Lipid Membrane Structure and Behavior

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: hybrid

OpenAlex ID: W2131136771

FWCI: 0.964

Cites: 4

Cited by: 37

Related to: 10