The Effects Of Oligofructose And Polydextrose On Metabolic Control Parameters In Type-2 Diabetes
Year: 2009
Type: article
Study design: Clinical Trial
Abstract: Objective: This study investigated the effects of oligofructose and polydextrose on metabolic control in Type-2 diabetes. Methodology: Twenty voluntary, postmenopausal, total cholesterol (TC)/HDL-cholesterol (HDL-C) ratios>4.5, female, Type-2 diabetes patients were included. The study was performed in four periods, with the baseline as the period one. In periods two and four, the patients consumed individual diabetic diets for eight weeks. In period three, they consumed 20g of oligofructose and polydextrose mixture in 40g sweetener (in powdered form), added to their diets for six weeks. Results: Prebiotic soluble fiber sources (oligofructose and polydextrose) significantly decreased fasting and postprandial (2-hour) blood glucose, glycosylated hemoglobin, TC, LDL-cholesterol (LDL-C), TC/HDL-C and LDL-C/HDL-C ratios, triglyceride, VLDL-cholesterol, lipoprotein (a), systolic and diastolic blood pressures (p<0.001), apolipoprotein B (p<0.05), and increased HDL-C, insulin (p<0.05), and C-peptide levels (p>0.05) compared to the initial values, respectively. Conclusion: Individual diabetic diets supplemented with prebiotics improved metabolic control in Type-2 diabetes.
Language: English
Subfield: Nutrition and Dietetics
Field: Nursing
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W2131299876