Year: 2014
Type: article
Abstract: BACKGROUND: There is a need for more Comparative Effectiveness Research (CER) on Chinese medicine (CM) to inform clinical and policy decision-making. This document aims to provide consensus advice for the design of CER trials on CM for researchers. It broadly aims to ensure more adequate design and optimal use of resources in generating evidence for CM to inform stakeholder decision-making. METHODS: The Effectiveness Guidance Document (EGD) development was based on multiple consensus procedures (survey, written Delphi rounds, interactive consensus workshop, international expert review). To balance aspects of internal and external validity, multiple stakeholders, including patients, clinicians, researchers and payers were involved in creating this document. RESULTS: Recommendations were developed for "using available data" and "future clinical studies". The recommendations for future trials focus on randomized trials and cover the following areas: designing CER studies, treatments, expertise and setting, outcomes, study design and statistical analyses, economic evaluation, and publication. CONCLUSION: The present EGD provides the first systematic methodological guidance for future CER trials on CM and can be applied to single or multi-component treatments. While CONSORT statements provide guidelines for reporting studies, EGDs provide recommendations for the design of future studies and can contribute to a more strategic use of limited research resources, as well as greater consistency in trial design.
Source: Trials
Authors: Collaborators, Claudia M Witt, Mikel Aickin, Daniel Cherkin, Chun Tao Che, Charles Elder, Andrew Flower, Richard Hammerschlag, Jian-Ping Liu, Lixing Lao, Steve Phurrough, Cheryl Ritenbaugh, Lee Hullender Rubin, Rosa Schnyer, Peter M Wayne, Shelly Rafferty Withers, Bian Zhao-Xiang, Jeanette Young, Brian M Berman
Institutions: University Hospital Zurich, University of Arizona, Kaiser Permanente Washington Health Research Institute, University of Illinois Chicago, Kaiser Permanente, Kaiser Permanente Center for Health Research, University of Southampton, Oregon College of Oriental Medicine, Beijing University of Chinese Medicine, University of Maryland Medical Center, Centers for Medicare and Medicaid Services, The University of Texas at Austin, Brigham and Women's Hospital, Harvard University, Osher Center for Integrative Medicine, Hong Kong Baptist University, University of Maryland, Baltimore
Language: English
Topic: Delphi Technique in Research
Subfield: Sociology and Political Science
Field: Social Sciences
Domain: Social Sciences
Open Access status: gold
Estimated APC paid: $2,790
OpenAlex ID: W2131327422