Work

Predictive Value of Admission Hemoglobin A1c on Inpatient Glycemic Control and Response to Insulin Therapy in Medicine and Surgery Patients With Type 2 Diabetes

Year: 2015

Type: article

Abstract: High hemoglobin A1c (A1C) levels are associated with poor clinical outcomes in hospitalized patients. Recent guidelines have recommended performing A1C measurements in hospitalized patients with hyperglycemia to differentiate between stress hyperglycemia and undiagnosed diabetes, to assess the level of glycemic control prior to admission in patients with diabetes, and to tailor appropriate diabetes therapy regimens at hospital discharge (1). To study the predictive role of admission A1C on inpatient glycemic control in medical and surgical hospitalized patients with type 2 diabetes, we combined inpatient data from four randomized controlled trials of patients treated with a basal-bolus insulin regimen (2–5). We adopted the definition of optimal glycemic control as a combination of blood glucose (BG) levels below 180 mg/dL without hypoglycemia (BG <70 mg/dL) after 24 h of insulin therapy. Logistic regression models were used to evaluate the …

Source: Diabetes Care

DOI: 10.2337/dc15-1835