Work

Towards an Ontological Representation of Resistance: The Case of MRSa

Year: 2009

Type: preprint

Abstract: This paper addresses a family of issues surrounding the biological phenomenon of resistance and its representation in realist ontologies. Resistance terms from various existing ontologies are examined and found to be either overly narrow, inconsistent, orotherwise problematic. We propose a more coherent ontological representation using the antibiotic resistance in Methicillin-Resistant Staphylococcus aureus (MRSa) as a case study.

Source: Nature Precedings

DOI: 10.1038/npre.2009.3474.1

Authors: Albert Goldfain, Lindsay Cowell, Barry Smith

Institutions: Duke Medical Center, University at Buffalo, State University of New York

Language: English

Topic: Biomedical Text Mining and Ontologies

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: diamond

Funder: National Institutes of Health

OpenAlex ID: W2131465295

Cites:

Cited by: 5

Related to: 10