Work

The Role of Surface Functionality on Acute Cytotoxicity, ROS Generation and DNA Damage by Cationic Gold Nanoparticles

Year: 2010

Type: article

Abstract: A poisoned chalice? Surface functionalization of 2 nm gold nanoparticles is an important determinant of their acute toxicity and genotoxicity. These attributes need to be considered for their use as carriers, and provide new direction for the design of therapeutics.

Source: Small

DOI: 10.1002/smll.201000463

Authors: Apiwat Chompoosor, Krishnendu Saha, Partha S. Ghosh, Dylan J. Macarthy, Oscar R. Miranda, Zheng‐Jiang Zhu, Kathleen F. Arcaro, Vincent M. Rotello

Institution: University of Massachusetts Amherst

Language: English

Topic: Gold and Silver Nanoparticles Synthesis and Applications

Subfield: Electronic, Optical and Magnetic Materials

Field: Materials Science

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: green

Funders: Center for Hierarchical Manufacturing, National Science Foundation, National Institute of General Medical Sciences

Awards: G3337567008, Rapid Multi-Channel Serum Profiling for Cardiac Disease using Fluorescent Nanosensors

OpenAlex ID: W2131465607

FWCI: 6.302

Cites: 40

Cited by: 288

Related to: 10