Work

Repeated presentation of Graves' disease as a manifestation of immune reconstitution syndrome in an HIV-infected patient taking HAART: case report.

Year: 2013

Type: article

Abstract: An HIV-infected patient who experienced immune reconstitution after highly active antiretroviral therapy (HAART) (increase in CD4 T-cell count from 84/mm3 to 310/mm3) presented with severe Graves' disease twice, after commencing and recommencing HAART. At the first episode of Graves' disease, 21 months after the introduction of HAART, the symptoms of thyroid dysfunction vanished without any specific treatment, but were associated with termination of taking HAART. At the second episode, 5 years after recommencing HAART, the patient continued taking HAART and commenced antithyroid therapy with thiamazole. Graves' disease developed after a long period, while the patient was in good condition and when complications resulting from HAART were not expected. No features of any autoimmune disease were diagnosed before HAART initiation.

Source: PubMed

Authors: Klaudija Visković, Lorna Stemberger, Zoran Brnić, Josip Begovac

Institution: University Hospital for Infectious Diseases "Dr Fran Mihaljevic"

Language: English

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2131914792

FWCI: 0.909

Cites: 7

Cited by: 9

Related to: 10