Work

Presence of Plasmid-Mediated Quinolone Resistance in Klebsiella pneumoniae Isolates Possessing bla KPC in the United States

Year: 2008

Type: article

Abstract: The presence of plasmid-mediated quinolone resistance genes [i.e., qnrA, qnrB, qnrS, aac(6')-Ib-cr, and qepA] was evaluated among 42 bla(KPC)-containing Klebsiella pneumoniae isolates collected in the eastern United States. One isolate carried the bla(KPC-3) and qnrB19 genes on the same conjugative plasmid, whereas another carried the bla(KPC-3) and qnrA1 genes on separate plasmids.

Source: Antimicrobial Agents and Chemotherapy

DOI: 10.1128/aac.00158-08

Authors: Andrea Endimiani, Lenore L. Carias, Andrea M. Hujer, Christopher R. Bethel, Kristine M. Hujer, Federico Perez, Rebecca A. Hutton, William R. Fox, Geraldine S. Hall, Michael R. Jacobs, David L. Paterson, Louis B. Rice, Stephen G. Jenkins, Fred C. Tenover, Robert A. Bonomo

Institutions: Louis Stokes Cleveland VA Medical Center, University Hospitals Cleveland Medical Center, Case Western Reserve University, Cleveland Clinic, University of Pittsburgh Medical Center, Centers for Disease Control and Prevention

Language: English

Topic: Antibiotic Resistance in Bacteria

Subfield: Molecular Medicine

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

Funder: National Institute of Allergy and Infectious Diseases

Award: Challenges in beta-Lactamase Mediated Resistance

OpenAlex ID: W2131992971

FWCI: 5.087

Cites: 17

Cited by: 99

Related to: 10