Work

Hippocampal volume and 2-year outcome in depression

Year: 2008

Type: article

Abstract: Although the hippocampus has been found to be smaller in people with depression, the clinical relevance of this is unclear. We investigated hippocampal volume (using high-resolution magnetic resonance imaging) and 2-year outcome in 57 patients with major depression. The left and right hippocampal volumes of patients with a depression relapse were significantly smaller than those of healthy controls. Our results support the hypothesis that the hippocampus is crucial in the outcome of depression.

Source: The British Journal of Psychiatry

DOI: 10.1192/bjp.bp.107.040378