Work

PDZBase: a protein–protein interaction database for PDZ-domains

Year: 2004

Type: article

Abstract: SUMMARY: PDZBase is a database that aims to contain all known PDZ-domain-mediated protein-protein interactions. Currently, PDZBase contains approximately 300 such interactions, which have been manually extracted from > 200 articles. The database can be queried through both sequence motif and keyword-based searches, and the sequences of interacting proteins can be visually inspected through alignments (for the comparison of several interactions), or as residue-based diagrams including schematic secondary structure information (for individual complexes).

Source: Bioinformatics

DOI: 10.1093/bioinformatics/bti098

Authors: Thijs Beuming, Lucy Skrabanek, Masha Y. Niv, Piali Mukherjee, Harel Weinstein

Institutions: Cornell University, Weill Cornell Medicine

Language: English

Topic: Protein Structure and Dynamics

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: bronze

Funders: National Institutes of Health, National Institute on Drug Abuse

Awards: G4064322281, MOLECULAR DETERMINANTS FOR THE ACTION OF HALLUCINOGENS, Hallucinogens and 5-HT Receptors: Mechanisms and Effects