P21.08: Primary study of Doppler ultrasound in screening the congenital cardiac defects between 11 + 0 and 14 + 6 weeks' gestation
Year: 2012
Type: conference-abstract
Abstract: To observ the fetal cardial structure and characters of endocardiac and extracardiac haemodynamics parameters at the end of first trimester and the early of second trimester by 2-dimensional ultrasound and Doppler ultrasound, evaluate the value of Doppler ultrasound in screening the congenital cardiac defects (CCD). General transabdominal ultrasonic exam was performed between 11 + 0 and 14 + 6 weeks' gestation. Measure the thickness of Nuchal Translucency (NT) or soft tissue of neck, observe the fetal cardiac structure, and measure the blood flow of mitral valve, tricuspid valve and ductus venosus. 335 fetuses were normal. 9 fetuses with increased NT thickness or soft tissue. 5 cases were terminated in first or second trimester: 1 fetus was diagnosed the persistent arterial trunk (PAT) in 13 gestational week and confirmed by autospy, 2 fetuses were found with extracardial abnormalities, 2 fetuses were aborted before 14 weeks' gestation. 4 fetuses without cardiac defects were delivered on full term. The early diastolic time (EADT) shorter than the end diastolic time (ENDT) in normal fetus, there is no significant difference between left and right ventricles. Increased PI, RI, S/D of ductus venouses were observed in fetus with thickened NT and without CCD. Endocardiac and extracardiac hemodynamics parameter of the fetus with PAT are different from normal fetus. With the increasing of visualization of fetal heart after 13 weeks' gestation, the fetus with the high risk of CCD could be performed the early fetal echocardiography exam for screening the severe CCD. To analyze the changes of endocardiac hemodynamics parameters, and observe the waveform of ductus venosus. The diagnosis of CCD should be cautious if the cardiac abnormal structure is only observed in 2 dimentional ultrasound and there is no obvious changes in endocardiac and extracardiac hemodynamics parameters.
DOI: 10.1002/uog.12057
Institution: Capital Medical University
Language: English
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W2133173133