Reduced phosphocholine and hyperpolarized lactate provide magnetic resonance biomarkers of PI3K/Akt/mTOR inhibition in glioblastoma
Work
Year: 2011
Type: article
Abstract: The phosphatidylinositol-3-kinase/Akt/mammalian target of rapamycin (PI3K/Akt/mTOR) signaling pathway is activated in more than88% of glioblastomas (GBM). New drugs targeting this pathway are currentl... more
Source: Neuro-Oncology
Authors Humsa S. Venkatesh, Myriam M. Chaumeil, Christopher Ward, Igor Yu. Kogan, C. David James +1 more
Cites: 51
Cited by: 90
Related to: 10
FWCI: 3.37
Citation percentile (by year/subfield): 94.27
Subfield: Spectroscopy
Field: Chemistry
Domain: Physical Sciences
Sustainable Development Goal Good health and well-being
Open Access status: bronze